Principal Investigator

M. SERDAR ÇELEBİ M. Serdar Çelebi is an experienced professor with a demonstrated history of working in the higher education, research, and high technology industry. Skilled in mathematical modeling, paralel numerical algorithms, multi-physics, multi-phase, multi-scale computer simulations, high performance computing, advanced programming, computer aided geometric modeling, biomechanics, and advance fluid dynamics. He has a strong background in engineering sciences and extensive professional and administrative experience.  Dr. Çelebi is currently a faculty member of Computational Science and Engineering Department at Istanbul Technical University. He served as a program coordinator, department head, dean of Informatics Institute, and founding project coordinator and director of UHeM (National Center for High Performance Computing). Dr. Çelebi is also one of the founders of Computational Science and Engineering Department in ITU. Personal Website: https://web.itu.edu.tr/mscelebi/  Email: mscelebi@itu.edu.tr

Postdoctoral Researchers

REZA DARYANİ Reza Daryani earned his Ph.D. in 2024 and is currently working as a postdoctoral researcher at Istanbul Technical University. His research focuses on cardiovascular computational modeling and fluid-structure interaction (FSI) simulations, with a particular emphasis on heart valve dynamics. Email: daryani@itu.edu.tr

Graduate Students

	E. CENK ERSAN E. Cenk Ersan is a PhD candidate and research assistant in the Computational Science and Engineering program at Istanbul Technical University, Informatics Institute. He received his B.Sc and M.Sc degrees in mechanical engineering. His research interests encompass computational fluid dynamics (CFD), numerical simulations, fluid mechanics, and the application of these techniques in biomedical engineering. Email: ersane@itu.edu.tr
	HACER DUZMAN Hacer Duzman is a PhD student and research assistant in the Computational Science and Engineering program at Istanbul Technical University, Informatics Institute. She holds a B.Sc degree in Biomedical Engineering and a M.Sc degree in Computational Science and Engineering. Her research focuses on medical image computing, cardiovascular blood flow modeling and simulation, and biomechanics. The ultimate goal of her research is to develop effective solutions to improve clinical outcomes and the lives of individuals suffering from cardiovascular diseases. Email: duzman21@itu.edu.tr
	MÜGE YAREN YAŞARTÜRK Müge Yaren Yaşartürk is a PhD student in the Computational Science and Engineering program at Istanbul Technical University and research assistant at Computer Engineering in Istanbul Beykent University. Email: yasarturk20@itu.edu.tr, mugeyarenyasarturk@gmail.com
	AHMET CAN TEKELİ Ahmet Can Tekeli's background in Bioengineering has had an unexpected influence on his passion for software development. This interdisciplinary experience has allowed him to approach problems from a unique perspective and develop more creative solutions. He is currently pursuing his PhD in Istanbul Technical University, Computational Science and Engineering. He works as a research assistant at Medeniyet University. Email: tekeli24@itu.edu.tr
	AFRAH FAREA Afrah Farea is a PhD student in the Computational Science and Engineering Department at Istanbul Technical University. She holds a bachelor's degree in software engineering and a master's degree in computer engineering, as well as a specialization in computational science and engineering. Her primary research focuses on machine learning, quantum computing, and high-performance computing. Email: afrah.nacib@gmail.com

Masters Students

EMİRHAN YİĞİT Emirhan Yiğit is a Master's student in the Computational Science and Engineering program at Istanbul Technical University. His work focuses on numerical modeling, finite element analysis, and high-performance computing. He holds a Bachelor's degree in Mechanical Engineering from ITU. With an early interest in numerical methods and simulation, he gained research experience at Computational Modeling and Simulation Lab through finite element modeling of aortic valve biomechanics. He is currently working on the development of computational models for heart and venous valve mechanics, with a focus on structural dynamics and efficient simulation workflows.               Email: yigitem19@itu.edu.tr

Undergraduate Students

	ASİYE TANKO Asiye is a bachelor's degree candidate in the Biomedical Engineering program of Istanbul Medipol University. She is currently pursuing a research internship at Istanbul Technical University's Informatics Institute Computational Modelling and Simulation Lab with a focus on the segmentation of healthy and diseased coronary arteries using manual methods and semi-automatic AI-mediated techniques. Email: asiye.tanko@std.medipol.edu.tr
	EKREM ŞİMŞEK Ekrem Şimşek is an undergraduate student in Aeronautical Engineering at Istanbul Technical University. His research interests include computational fluid dynamics (CFD) and fluid–structure interaction (FSI). Email: simsekek22@itu.edu.tr
	M. MERT DİNÇER M. Mert Dinçer is a mechanical engineering student at Yıldız Technical University. His research interests are Computational Fluid Dynamics, Numerical Analysis, Machine and Deep Learning Algorithms. Email: muhammet.dincer@std.yildiz.edu.tr
	EMİRHAN İNAN Emirhan Inan is currently pursuing two Bachelor's Degrees at Istanbul Bilgi University in Electrical & Electronics Engineering and Computer Engineering. His research objectives are learning and applying cardiovascular simulations, utilizing open-source software like openCARP, Chaste, and SimVascular to model transmembrane voltage dynamics and ion channel behavior. His work involves numerical solutions of stiff systems of ordinary differential equations governing ionic currents in cardiac myocytes, simulating action potential propagation through cardiac tissue, and extending to the construction of Purkinje fiber networks. He is particularly adamant about the integration of electrophysiological modeling with real-time clinical applications, especially the RF catheter ablation. Drawing on his background in electromagnetics and signal processing, Emirhan aims to bridge detailed electric simulations in the biodomain with therapeutic energy delivery models in the bidomain framework, enabling more accurate and patient-specific medical procedures to treat arrhythmias or other heart ailments. Personal Website: https://www.emirhaninan.com  Email: emirhan.inan814@gmail.com

Clinical Consultant – Cardiology

ASSOC. PROF. ŞÜKRÜ ARSLAN Şükrü Arslan is an Associate Professor in the Department of Cardiology at the Istanbul University-Cerrahpaşa Cardiology Institute. Dr. Arslan currently serves as the Clinical Consultant in the TÜBİTAK 1001 research project titled “Hemodynamic Simulation of Supra Left Ventricular Heart Blood Flow Coupled with Coronary Arteries”, where he provides clinical insight to support the development and validation of advanced cardiovascular models. Email: sukru.arslan@iuc.edu.tr

Alumni

1. Reza DARYANİ, Hemodynamic characterization of heart and venous valves based on multi-phase blood flow and FSI modelling, Ph.D., ITU Faculty of Mechanical Engineering, 2024.
2. Hızır Can BAYRAM, Reproducibility Quantification for Graph Neural Networks, Master, Computer Engineering, Faculty of Computer and Informatics, ITU, February 2024.
3. Müge Yaren YAŞARTÜRK, Design Process, Manifacturing and Material Characterization of a Prosthetic Polymer Aortic Heart Valve, Master, Computational Science and Engineering, Informatics Institute, ITU, February 2024.
4. Hacer DUZMAN, Patient-Specific In-Slico Hemodynamics Characterization of the AAOCA Anomaly in Left Coronary Artery Network, Master, Computational Science and Engineering, Informatics Institute, ITU, February 2024.
5. Erke ARIBAŞ, A 3D Simulation of Human Artery and Vein System Using Two-Phase Blood Flow Coupled with a Thermal RBC Aggregation Model, Ph.D., Informatics Institute, ITU, September 2020.
6. Merve NARİNSES, Rapture Status Investigation of Patient Specific Cerebral Aneurysms by Analysing Hemodynamic Factors Using Computational Fluid Dynamics, Master, Informatics Institute, ITU, December 2018.
7. Afrah FAREA, On the Anaylysis and Evaluation of Sparse Hybrid Linear Solvers, Master, Informatics Institute, ITU, June 2018.
8. Meysam ABOUTALEBI, Heterogeneous Computing for Multi-Phase Blood Flow Simulations, Master, Informatics Institute, ITU, June 2018.
9. Utkan ÇALIŞKAN, Two-Phase Blood Flow Modeling for Deep Vein Thrombosis, Master, Informatics Institute, ITU, July 2017.
10. İbrahim ÖZKÜÇÜK, Quasi-Newton and Artificial Compressibility Based Partitioned Algorithms for Strongly Coupled Fluid Structure Interactions, Master, Informatics Institute, ITU, July 2017.
11. Gürsan ÇOBAN, Biomechanical Modeling of Growth and Remodeling Process in Soft Biological Tissue, Ph.D., Informatics Institute, ITU, September 2016.
12. Halil Ertürk ESEN, A Novel Multivariate Stochastic Volatility Model and Estimation With GPU Computing, Ph.D., (co-advising with Prof. Dr. Burç ULENGİN), Informatics Institute, ITU, June 2016.
13. Ahmet Cem MERCAN, An Approach for the Chest Tube Detection in Chest Radiographs Using Convolutional Neural Network, Ph.D., Informatics Institute, ITU, Feb. 2015.
14. Yağmur GÜLKANAT, Modeling of Blood Flow and Vessel Wall Interaction for Stenoised Coronary Arteries, Master, Informatics Institute, ITU, June 2014.
15. Şenol PİŞKİN, A Numerical Three Dimensional Blood-Artery Wall Interaction Model For Human Carotid Artery and Its Applications, Ph.D., Informatics Institute, ITU, Sept. 2013.

Previous Project Scholars

1. Okan Özdeş, Undergraduate Student, Department of Civil Engineering, Faculty of Engineering, Çukurova University. Project Scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves". Supported by TUBITAK BİÇABA Scholarship Program.
2. Suna Deniz, Undergraduate Student, Department of Aeronautical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.
3. Emirhan Yiğit, Undergraduate Student, Department of Mechanical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.
4. Furkan Cömert, Undergraduate Student, Department of Mechanical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.
5. Orkun Mert Üstün, Undergraduate Student, Department of Mechanical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.