Principal Investigator

M. Serdar Çelebi
M. SERDAR ÇELEBİ

M. Serdar Çelebi is an experienced professor with a demonstrated history of working in the higher education, research, and high technology industry. Skilled in mathematical modeling, parallel numerical algorithms, multi-physics, multi-phase, multi-scale computer simulations, high performance computing, advanced programming, computer aided geometric modeling, biomechanics, and advance fluid dynamics. He has a strong background in engineering sciences and extensive professional and administrative experience.

Dr. Çelebi is currently a faculty member of Computational Science and Engineering Department at Istanbul Technical University. He served as a program coordinator, department head, dean of Informatics Institute, and founding project coordinator and director of UHeM (National Center for High Performance Computing). Dr. Çelebi is also one of the founders of Computational Science and Engineering Department in ITU.

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Postdoctoral Researchers

Reza Daryani
REZA DARYANİ

Reza Daryani earned his Ph.D. in 2024 and is currently working as a postdoctoral researcher at Istanbul Technical University. His research focuses on cardiovascular computational modeling and fluid-structure interaction (FSI) simulations, with a particular emphasis on heart valve dynamics.

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Graduate Students

E. Cenk Ersan
E. CENK ERSAN

E. Cenk Ersan is a PhD candidate and research assistant in the Computational Science and Engineering program at Istanbul Technical University, Informatics Institute. He received his B.Sc and M.Sc degrees in mechanical engineering. His research interests encompass computational fluid dynamics (CFD), numerical simulations, fluid mechanics, and the application of these techniques in biomedical engineering.

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Hacer Duzman
HACER DUZMAN

Hacer Duzman is a PhD student and research assistant in the Computational Science and Engineering program at Istanbul Technical University, Informatics Institute. She holds a B.Sc degree in Biomedical Engineering and a M.Sc degree in Computational Science and Engineering. Her research focuses on medical image computing, cardiovascular blood flow modeling and simulation, and biomechanics. The ultimate goal of her research is to develop effective solutions to improve clinical outcomes and the lives of individuals suffering from cardiovascular diseases.

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Müge Yaren Yaşartürk
MÜGE YAREN YAŞARTÜRK

Müge Yaren Yaşartürk is a PhD student in the Computational Science and Engineering program at Istanbul Technical University and a lecturer in the Information Security Technologies program at Istanbul Beykent University. She holds a B.Sc. degree in Biomedical Engineering and an M.Sc. degree in Computational Science and Engineering.

During her master’s studies, she focused on the design, manufacturing, and material characterization of a prosthetic polymeric aortic heart valve. Her current academic interests lie at the intersection of artificial intelligence in healthcare and computational biology, with an emphasis on developing data-driven and computational approaches to support biomedical research and clinical decision-making. Her long-term goal is to contribute to the development of intelligent and reliable computational systems that can enhance healthcare technologies and improve patient outcomes.

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Bayezid Özden
BAYEZİD ÖZDEN

Bayezid Özden is a senior civil and railway systems engineer with over twenty years of experience in railway infrastructure engineering, structural design, and large-scale project delivery. He currently serves as Deputy General Manager of Engineering at Yapıray Railway Construction Systems, where he oversees engineering, design, and production activities for trackwork technologies, including prefabricated sleepers and ballastless slab track systems for metro and high-speed railway projects.

He is pursuing a Ph.D. in Computational Science and Engineering at Istanbul Technical University. His research focuses on computational modeling of railway track dynamics and vehicle–track–infrastructure interaction, with particular emphasis on intelligent and data-driven methods, including physics-informed neural networks (PINNs). His academic interests lie at the intersection of railway engineering, structural dynamics, and scientific machine learning.

His work combines advanced numerical analysis with full-scale laboratory testing and field measurements to improve the performance, safety, and durability of railway systems. His professional and academic activities reflect an integrated approach to applied research and engineering practice in modern railway infrastructure.

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Masters Students

Emirhan Yiğit
EMİRHAN YİĞİT

Emirhan Yiğit is a Master's student in the Computational Science and Engineering program at Istanbul Technical University. His work focuses on numerical modeling, finite element analysis, and high-performance computing.

He holds a Bachelor's degree in Mechanical Engineering from ITU. With an early interest in numerical methods and simulation, he gained research experience at Computational Modeling and Simulation Lab through finite element modeling of aortic valve mechanics. He is currently working on the development of computational models for heart and venous valve mechanics, with a focus on efficient simulation workflows and GPU acceleration strategies for CFD simulations.

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Undergraduate Students

Alper Demircioğlu
ALPER DEMİRCİOĞLU

Alper Demircioğlu is an undergraduate student in Mechanical Engineering at Istanbul Technical University (ITU). His work focuses on the post-processing and visualization of computational simulation results, transforming numerical flow data into interactive three-dimensional representations.

Muhammed Ali Kulniyaz
MUHAMMED ALİ KULNİYAZ

Muhammed Ali Kulniyaz is an undergraduate student in Metallurgy and Materials Engineering at Yıldız Technical University (YTU). He is currently involved in research on multiscale computational modeling of cardiovascular diseases. His work focuses on developing Python-based Agent-Based Models (ABM) that integrate with Computational Fluid Dynamics (CFD) to simulate hemodynamically-driven atherosclerotic plaque progression. His academic interests lie at the intersection of computational materials science and mechanobiology, specifically bridging molecular-level mechanisms—such as lipid oxidation and membrane permeability—with macroscopic blood flow data to create predictive, physics-based models.

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bithanya_stajyer1 
BITHANYA ABRAHAM HAILE

Bithanya Haile is a 2nd-year Biomedical Engineering student at Samsun University. She is currently completing a summer research internship at ITU's Informatics Institute, supervised by Prof. Dr. Mustafa Serdar Çelebi and Yalçın Çökgel. Her work focuses on applying small language models to single-lead ECG signal analysis for cardiac condition classification.

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Clinical Consultant – Cardiology

Şükrü Arslan
ASSOC. PROF. DR. ŞÜKRÜ ARSLAN

Şükrü Arslan is an Associate Professor in the Department of Cardiology at the Istanbul University-Cerrahpaşa Cardiology Institute. Dr. Arslan currently serves as the Clinical Consultant in the TÜBİTAK 1001 research project titled “Hemodynamic Simulation of Supra Left Ventricular Heart Blood Flow Coupled with Coronary Arteries”, where he provides clinical insight to support the development and validation of advanced cardiovascular models.

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Alumni

  1. Afrah FAREA, Quantum Machine Learning Algorithms for the Solution of Partial Differential Equations, Ph.D., Computational Science and Engineering, Informatics Institute, ITU, 2026.
  2. Reza DARYANİ, Hemodynamic characterization of heart and venous valves based on multi-phase blood flow and FSI modelling, Ph.D., ITU Faculty of Mechanical Engineering, 2024.
  3. Hızır Can BAYRAM, Reproducibility Quantification for Graph Neural Networks, Master, Computer Engineering, Faculty of Computer and Informatics, ITU, February 2024.
  4. Müge Yaren YAŞARTÜRK, Design Process, Manifacturing and Material Characterization of a Prosthetic Polymer Aortic Heart Valve, Master, Computational Science and Engineering, Informatics Institute, ITU, February 2024.
  5. Hacer DUZMAN, Patient-Specific In-Slico Hemodynamics Characterization of the AAOCA Anomaly in Left Coronary Artery Network, Master, Computational Science and Engineering, Informatics Institute, ITU, February 2024.
  6. Erke ARIBAŞ, A 3D Simulation of Human Artery and Vein System Using Two-Phase Blood Flow Coupled with a Thermal RBC Aggregation Model, Ph.D., Informatics Institute, ITU, September 2020.
  7. Merve NARİNSES, Rapture Status Investigation of Patient Specific Cerebral Aneurysms by Analysing Hemodynamic Factors Using Computational Fluid Dynamics, Master, Informatics Institute, ITU, December 2018.
  8. Meysam ABOUTALEBI, Heterogeneous Computing for Multi-Phase Blood Flow Simulations, Master, Informatics Institute, ITU, June 2018.
  9. Utkan ÇALIŞKAN, Two-Phase Blood Flow Modeling for Deep Vein Thrombosis, Master, Informatics Institute, ITU, July 2017.
  10. İbrahim ÖZKÜÇÜK, Quasi-Newton and Artificial Compressibility Based Partitioned Algorithms for Strongly Coupled Fluid Structure Interactions, Master, Informatics Institute, ITU, July 2017.
  11. Gürsan ÇOBAN, Biomechanical Modeling of Growth and Remodeling Process in Soft Biological Tissue, Ph.D., Informatics Institute, ITU, September 2016.
  12. Halil Ertürk ESEN, A Novel Multivariate Stochastic Volatility Model and Estimation With GPU Computing, Ph.D., (co-advising with Prof. Dr. Burç ULENGİN), Informatics Institute, ITU, June 2016.
  13. Ahmet Cem MERCAN, An Approach for the Chest Tube Detection in Chest Radiographs Using Convolutional Neural Network, Ph.D., Informatics Institute, ITU, Feb. 2015.
  14. Yağmur GÜLKANAT, Modeling of Blood Flow and Vessel Wall Interaction for Stenoised Coronary Arteries, Master, Informatics Institute, ITU, June 2014.
  15. Şenol PİŞKİN, A Numerical Three Dimensional Blood-Artery Wall Interaction Model For Human Carotid Artery and Its Applications, Ph.D., Informatics Institute, ITU, Sept. 2013.

Previous Project Scholars & Summer Interns

  1. Mehmet Eren Akgül, Undergraduate Student, Computer Engineering at Istanbul University-Cerrahpasa. Project scholar in "Hemodynamic Simulation of Supra Left Ventricular Heart Blood Flow Coupled with Coronary Arteries" supported by TUBITAK STAR Scholarship Program.
  2. Tuğba Kütükçü, Undergraduate Student, Department of Biomedical Engineering, Yıldız Technical University, summer intern mentored by Hacer Duzman.
  3. Asiye Tanko, Undergraduate Student, Department of Biomedical Engineering, Istanbul Medipol University, summer intern mentored by Hacer Duzman.
  4. Emirhan İnan, Undergraduate Student, Electrical & Electronics Engineering and Computer Engineering, Istanbul Bilgi University, summer intern mentored by Prof. Dr. M. Serdar Çelebi.
  5. M. Mert Dinçer, Undergraduate Student, Department of Mechanical Engineering, Yıldız Technical University, summer intern mentored by E. Cenk Ersan.
  6. Ekrem Şimşek, Undergraduate Student, Department of Aeronautical Engineering, ITU, summer intern mentored by Dr. Reza Daryani.
  7. Okan Özdeş, Undergraduate Student, Department of Civil Engineering, Faculty of Engineering, Çukurova University. Project Scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves". Supported by TUBITAK BİÇABA Scholarship Program.
  8. Suna Deniz, Undergraduate Student, Department of Aeronautical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.
  9. Emirhan Yiğit, Undergraduate Student, Department of Mechanical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.
  10. Furkan Cömert, Undergraduate Student, Department of Mechanical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.
  11. Orkun Mert Üstün, Undergraduate Student, Department of Mechanical Engineering, ITU, Project scholar in "Computational Hemodynamic Modelling of Prosthetic Heart and Venous Valves", supported by TUBITAK STAR Scholarship Program.