This TUBITAK 1001-funded research project (Project No: 124M416) focuses on developing an integrated and physiologically realistic cardiovascular hemodynamic model. Spanning from February 2025 to February 2028, with a budget of 1,650,000 TL, the project brings together advanced simulation, clinical relevance, and emerging technologies to address critical challenges in cardiovascular medicine.

The model combines the coronary arteries, sinus of Valsalva, ascending and descending aorta, aortic arch, and carotid arteries within a single computational framework. It features non-Newtonian, two-phase blood flow; fully coupled two-way fluid–structure interaction (FSI) with multi-scale Windkessel and coronary lumped parameter models. Cardiac contraction and relaxation dynamics are also incorporated to reflect realistic flow behavior.

With the integration of VR/XR-based immersive technologies and 3D bioprinting, the project supports preoperative planning, diagnostic evaluation, and medical training by enabling both virtual and physical interaction with patient-specific anatomies. The project investigates seven key cardiovascular conditions including aortic dissection, coronary stenosis, LVOT abnormalities, and AF related ischemia.

Explore our journey in advancing cardiovascular research through high-fidelity modeling and interdisciplinary collaboration.

We are also currently seeking interns and volunteer undergraduate students who are eager to contribute to ongoing project and gain hands-on research experience in a dynamic academic environment.

Project Number: 124M416
Project Budget: 1.650.000 TL
Project Time: February 2025 - February 2028